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Traditional probe-type ultrasonic cell disruptors directly contact the sample, causing metal ion contamination and only allowing for the processing of one sample at a time, resulting in long experimental cycles. For multiple samples, the same probe needs to be repeatedly used, leading to potential sample cross-contamination. Since the depth of each probe insertion and the energy distribution of each ultrasonic wave is different, the repeatability and accuracy of experimental results are affected. In addition, due to the inability to use a closed system, the aerosols or foam generated during the ultrasonic process may spread to the environment, resulting in potential biological hazards. In contrast, the non-contact cup-type ultrasonic cell disruptor can simultaneously process 4-32 samples, improving experimental efficiency. There is no need for frequent probe operations, and each sample is contained in a separate fully sealed tube, avoiding cross-contamination. The use of a 4°C water bath ensures even distribution of ultrasonic energy and complete ultrasonic effects. The ultrasonic parameters can be flexibly adjusted, and the experimental steps are standardized, resulting in good experimental repeatability and high reliability of results. |